When you click on Device Manager link in the Tasks pane in Control Panel – System, Device Manager does not launch. However, you may be able to launch Device Manager via the Control Panel or using other methods.

This problem is caused by interference of one or more third-party shell extensions, implemented in the following registry locations:
ISOLATING THE SHELL EXTENSION
Inspecting and temporarily disabling each shell extension needs advanced skill level with Windows and the registry. Instead of working with the registry directly, you may use ShellExView, a freeware from Nirsoft.net to tackle this issue. See our detailed troubleshooting guide Right-click is slow or weird behavior caused by context menu handlers. It is suggested that you proceed directly to Method 2 in that page. This should help you isolate the context menu handler shell extension that’s causing the problem.
Editor’s note: If the above info has helped you, feel free to leave a comment with your findings so that it helps other readers who’re experiencing this problem.
SEE ALSO
"Play All" link in the Common Tasks does not work
Problem caused by adding Copy To and Move To as context menu entries
Manage the context-menu entries for files, folders, drives and Namespace objects
Working with Context Menus, Open-with and Send To menu
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Many thanks for your help. This problem was bugging me for months. My problem was caused by the shell extension Compare It (by Grig software).
Thank You. Great Article. Sorted Problem caused by poweriso context menu.
I followed method 2 from above and was able to disable the one context menu file which caused the issue. Many thanks for your help.
Thanks a million! I work at a Tech Support center and this article saved me hours or maybe days of research. It was probably caused by the Acer eSecurity shell extension.
copy handler one of the programs
after uninstalling problem resolved
Thank you, I was having this exact problem with Device Manager not opening when I would click on the hyperlink in the Tasks Pane.
John’s suggestion works great also.
Easiest Way – Click Start -> in the “Start Search” box type “Dev” (DO NOT HIT ENTER) and wait for list to show up then click Device Manager