Symptom
When you try to install the Windows Installer Cleanup Utility in Windows Vista, the following error may appear:
Script: C:\Users\Ramesh\AppData\Local\Temp\IXP000.TMP\StartMsi.vbs
Line: 17
Char: 1
Error: Permission denied
Code: 800A0046
Source: Microsoft VBScript runtime error
Cause
With the User Account Control (UAC) enabled in Windows Vista, you may be denied write access to the Program Files directory and its sub-directories by default. The error above occurs when the Windows Installer Cleanup Utility's setup script (StartMSI.vbs) attempts to copy the extracted files from the Temporary folder to the C:\Program Files\MSECache\WICU3 folder.
Resolution
To resolve the problem, you need to install the Windows Installer Cleanup Utility as administrator. To do so, right-click the setup file (msicuu2.exe) and choose Run as Administrator. If you are prompted for an administrator password or for confirmation, type your password, or click Continue.